This book constitutes selected papers presented at the 16th International Conference on Service Science, ICSS 2023, held in Harbin, China, in May 2023. 
The 36 full papers and 2 short papers presented were thoroughly reviewed and selected from the 71 submissions. They are organized in the following topical sections: serverless edge computing; edge services reliability; intelligent services; service application; knowledge-inspired service; service ecosystem; graph-based service optimization; AI-inspired service optimization.