More than three hundred infectious diseases have emerged or remerged in new territory during the past fifty years, and 90 percent of epidemiologists expect that one of them will cause a disruptive, deadly pandemic sometime in the next two generations. To reveal how that might happen, Sonia Shah tracks each stage of cholera's dramatic journey from harmless microbe to world-changing pandemic, from its 1817 emergence in the South Asian hinterlands to its rapid dispersal across the nineteenth-century world and its latest beachhead in Haiti. She reports on the pathogens following in cholera's footsteps, from the MRSA bacterium that besieges her own family to the never-before-seen killers emerging from China's wet markets, the surgical wards of New Delhi, the slums of Port-au-Prince, and the suburban backyards of the East Coast. By delving into the convoluted science, strange politics, and checkered history of one of the world's deadliest diseases, Pandemic reveals what the next epidemic might look like - and what we can do to prevent it.