This book focuses on low-carbon sustainable cement production, performance, environmental efficiency, and other topics linked to calcined clays for sustainable concrete. It comprises select proceedings of the International Conference on Calcined Clays for Sustainable Concrete 2022, which was held at École Polytechnique Fédérale de Lausanne (EPFL)—Switzerland. The contents of this book focus on the influence of processing and clay mineralogy on the reactivity and rheology of calcined clay systems, Portland-calcined clay-limestone systems: hydration, durability, and performance, and calcined clay-alkali systems: hydration, durability, and performance, etc. This book can serve as a useful reference to researchers, academicians, and practitioners alike.