This book features a collection of high-quality, peer-reviewed research papers presented at the 10th International Conference on Innovations in Computer Science & Engineering (ICICSE 2022), held at Guru Nanak Institutions, Hyderabad, India, on 16–17 September 2022. It covers the latest research in data science and analytics, cloud computing, machine learning, data mining, big data and analytics, information security and privacy, wireless and sensor networks and IoT applications, artificial intelligence, expert systems, natural language processing, image processing, computer vision, and artificial neural networks.