The book offers valuable insights into research related to Industry 4.0 applications that utilize artificial intelligence (AI), machine learning (ML), and the Industrial Internet of Things (IIoT). Industry 4.0, also known as the Fourth Industrial Revolution, includes disruptive technologies such as the Internet of Things (IoT), robotics, virtual reality (VR), VLSI architecture, and AI, all of which are transforming modern society and manufacturing practices. This book addresses various aspects of smart industrial application design strategies and their effects on next-generation systems, including quantum computing, edge computing, IoT, cybersecurity, nano-communications, and robotic automation. The application of AI, machine learning techniques, and IoT is anticipated to improve the performance of automated and controlled systems. Intended as a resource for academics, researchers, and professionals in the fields of AI and ML, the content also explores their applications within the industrial revolution and the influence of VLSI on the global market. Additionally, the book serves as a reference for developing sustainable engineering solutions to address various global industrial challenges.