One of the ways of making drug delivery more efficient is the use of nanosystems for targeted delivery and timed release. This new monograph in the ASME-Momentum Press series on Biomedical & Nanomedical Technologies will explore the latest research on nanoparticulate delivery systems for the immune modulating agent, GMDP (N-acetylglucosaminyl-N-acetylmuramyl-Lisoglutamine), an important component in cell wall structure and receptors. Silica nanoparticles in particular have shown great promise in enhanced delivery of drugs targeted at this cellular wall component.