The large-scale structure of the Universe and systems Clusters, and Groups of galaxies are topics like Superclusters, They fully justify the meeting on "Clusters of great interest. and Groups of Galaxies". The topics covered included the spatial distribution and the clustering of galaxies; the properties of Superclusters, Clusters and Groups of galaxies; radio and X-ray observations; the problem of unseen matter; theories concerning hierarchical clustering, pancakes, cluster and galaxy formation and evolution. The meeting was held at the International Center for Theoretical Physics in Trieste (Italy) from September 13 to September 16, 1983. It was attended by about 150 participants from 22 nations who presented 67 invited lectures (il) and contributed papers (cp), and 45 poster papers (pp). The Scientific Organizing Committee consisted of F. Bertola, P. Biermann, A. Cavaliere, N. Dallaporta, D. Gerba1, M. Hack, J . V . Peach, D. Sciama (Chairman), G. Setti, M. Tarenghi. We are particularly indebted to D. Sciama, A. Cavaliere and F. Bertola for their work of coordination. We were acting as the three members of the Local Organizing Committee. Moreover, we are pleased to thank the Chairmen of the Sessions (M. Hack, N. Da11aporta, G. Burbidge, B. Mills, M. Rees, P. Biermann, L.Z. Fang, L. Gouguenheim) for their valuable help.