This book is a collection of selected papers submitted to the 2022 International Conference on Intelligent Systems Design and Engineering Applications organized in Tokyo, Japan, May 13-15, 2022 (ISDEA2022). The book is organized according to the conference’s five major themes, including 1) Theory and Application of Intelligent Computing, 2) Intelligent Information System and Management Decision, 3) Artificial Intelligence and Robots, 4) Mechanical design and intelligent manufacturing and 5) Intelligent control and detection technology. ISDEA establishes a platform for researchers and scholars working in the field of intelligent systems design and engineering applications to present their newest research results, exchange innovative ideas, propose new models, as well as demonstrate advanced methodologies and novel design and systems.