Simulation is a widely used methodology in all the Applied Science disciplines. It provides a flexible, powerful and intuitive tool for investigating how to design a process or system, and how to maximize its efficiency. Simulation's effectiveness depends greatly on how well the simulation experiments are designed and analyzed. Design and Analysis of Simulation Experiments will focus on this crucial phase in the overall process of applying simulation. The book will include the best of both classic and modern methods of simulation experimentation, and as a result, it will provide a state-of-the-art treatment of the topic. This book will be the standard reference book on the topic for both researchers and sophisticated practitioners in the area, and it will be used as a textbook in courses or seminars focusing on this topic.