This unique compendium provides state-of-the-art computational methodology and applications in bioimage informatics. It covers cutting-edge technology developments in biological image analysis, where images come from new modalities and are often large scale, high throughput and high dimensional. The book reflects advances in intelligent algorithms for tasks such as biological image segmentation, reconstruction, and object tracking.Contributed by world renowned researchers, this useful reference text presents case studies that can potentially help readers find approaches and resources to address their imminent scientific problems.