This book contains papers presented at the 2nd International Conference on Cognitive based Information Processing and Applications (CIPA) in Changzhou, China, from September 22 to 23, 2022. The book is divided into a 2-volume series and the papers represent the various technological advancements in network information processing, graphics and image processing, medical care, machine learning, smart cities. It caters to postgraduate students, researchers, and practitioners specializing and working in the area of cognitive-inspired computing and information processing.