Here are the proceedings of the Falk Symposium 150, "Disease Progression and Disease Prevention in the Gastrointestinal Tract", held in Berlin, Germany, October, 2005. Pathogenic processes are described as well as primary and secondary prevention and treatment of disease. The symposium generated new perspectives on the various different pathogenic mechanisms in gastrointestinal organs. The book summarizes the state of the art in these different disease entities, as presented at the meeting.