In this book the pathophysiology, diagnosis, and therapy of most aspects of peptic ulcer disease are examined in detail. Covered are the pharmacology of the parietal cell and the latest hypotheses for the development of acid-peptic disease including epidermal growth factor, gastrin and other peptide hormones, fatty acids and prostaglandins, helicobacter pylori, and gastric acid hypersecretion including Zollinger-Ellison syndrome. The book also deals with the newer antisecretory medication such as omeprazole with a review of H2-receptor antagonists. Rounding off the subject are chapters on gastroesophageal reflux disease, upper GI endoscopy, and videoendoscopy including digital imaging. This volume addresses a wide range of physicians who are interested in all aspects of acid-peptic disease. What distinguishes this volume from others is the timely update on a number of important issues pertaining to acid-peptic disease. Not only does it review a number of topics that are of great interest at the present time, but it introduces a vast amount of new unpublished data.

Contributions by: S.B. Benjamin, G.M.A. Börsch, S.H. Caldwell, E.L. Cattau, M.J. Collen, J. Doppman, D.E. Fleischer, J.D. Gardener, D.Y. Graham, A. Guglietta, D. Hollander, C.W. Howden, R.H. Hunt, R.T. Jensen, D.A. Johnson, J.H. Lewis, P.N. Maton, R.W. McCallum, L.S. Miller, R.V. Nardi, I. Parikh, J.W. Rademaker, A.M. Rosen, G. Sachs, A. Tarnawski, J. Van Dam, B. Wallmark, M.M. Wolfe, P.N. Yakshe