This book presents the proceedings of the 24th International Conference Professional Culture of the Specialist of the Future. Professionals and experts in all fields need to be prepared to handle unfamiliar situations. Some of these are unexpected events that may occur quite suddenly out of the blue, and others may emerge in the course of technological development or predicted trends. In order to successfully confront the future, professionals therefore need to engage in hypothetical thinking as they entertain concrete scenarios or fictitious possibilities. Scientists and engineers lead the way when they employ thought experiments and systematically consider alternative realities. Educators come up with creative approaches to foster the “art of the as-if.” This highly interdisciplinary collection of 50 papers discusses the theoretical challenge of hypothetical thinking and presents practical strategies for its promotion.