This volume presents select proceedings of the International Conference on Sustainable Advanced Computing (ICSAC – 2021). It covers the latest research on a wide range of topics spanning theory, systems, applications, and case studies in advanced computing. Topics covered are machine intelligence, expert systems, robotics, natural language processing, cognitive science, quantum computing, deep learning, pattern recognition, human-computer interface, biometrics, graph theory, etc. The volume focuses on the novel research findings and innovations of various researchers. In addition, the book will be a promising solution for new generation-based sustainable, intelligent systems that are machine and human-centered with modern models and appropriate amalgamations of collaborative practices with a general objective of better research in all aspects of sustainable advanced computing.