This book gathers selected papers from the 28th International Cryogenic Engineering Conference and International Cryogenic Materials Conference 2022 (ICEC28-ICMC 2022), held virtually in Hangzhou, China on 25-29 April 2022, due to COVID-19 pandemic. Highlighting the latest findings on cryogenic engineering and cryogenic materials, it covers topics including: large-scale cryogenic components, processes and systems for refrigeration, separation, and liquefaction of cryogenic fluids, small-scale cryocoolers, cryogenic space applications, thermal insulation, thermal-physical properties of cryogenic fluids and materials, superconducting materials, devices, systems and applications, etc. The book offers valuable information and insights for academic researchers, engineers in the industry, and operators in the cryogenic field.