This book is about Case-Based Collaborative Learning (CBCL) for medical educators. CBCL combines elements from team-, case- and problem-based based learning using a flipped classroom model. This book presents a detailed “how to” guide on how to create CBCL classroom materials, how to facilitate vivid discussions, and how to support students and faculty in a CBCL curriculum. The first chapter explores the CBCL method in context of established educational principles. The second chapter provides a step-wise guide to creating CBCL teaching materials from scratch or adapting existing resources. Chapter three discusses how to support both - faculty and students - in making the most out of in-class case discussions. The last chapter explores modifications to the CBCL method that have evolved over time in adapting to teaching remotely, as well as promoting self-directed learning skills in students. While originally developed in context of undergraduate medical education, the CBCL method is of interest to anyone in higher education that values flipped classroom methods and discussion-based teaching.