The Fifteenth International Workshop on Maximum Entropy and Bayesian Meth- ods was held July 31-August 4, 1995 in Santa Fe, New Mexico, USA. St. John's College, located in the foothills of the Sangre de Cristo Mountains, provided a congenial setting for the Workshop. The relaxed atmosphere of the College, which was thoroughly enjoyed by all the attendees, stimulated free-flowing and thought- ful discussions. Conversations continued at the social events, which included a reception at the Santa Fe Institute, a New Mexican dinner at Richard Silver's home, and an excursion to Los Alamos that ended with a mixed grill at FUller Lodge, the main hall of the former Los Alamos Ranch School. This volume represents the Proceedings of the Workshop. Articles on the tra- ditional theme of the Workshop, application of the maximum-entropy principle and Bayesian methods for statistical inference in diverse areas of scientific re- search, are contained in these Proceedings. As is tradition, the Workshop opened with a tutorial on Bayesian methods, lucidly presented by Peter Cheeseman and Wray Buntine (NASA AMES, Moffett Field). The lecture notes for their tutorial are available on the World Wide Web at http://bayes .lanl. gov / "'maxent/. In addition, several new thrusts for the Workshop are described below.