This book presents the latest scientific advancements and innovative R&D solutions for the treatment of liquid radioactive waste in the context of practical threats in Ukraine. It includes research and engineering insights from the International Conference “Liquid Radioactive Waste Treatment: Ukrainian Context” (LWRT 2022), which was held in Kyiv, Ukraine on June 30, 2022. This publication covers a wide range of topics related to the treatment and management of radioactive waste, with a particular emphasis on safety considerations. The included articles also explore various aspects of environmental engineering and innovative R&D solutions, as well as the sustainability challenges associated with radioactive waste in the context of postwar reconstruction efforts. The contributions featured in this publication were selected through a rigorous international peer-review process. The carefully curated collection of articles showcases a diverse range of exciting ideas, poised to inspire novel research directions and stimulate interdisciplinary collaborations.