This policy-oriented jurisprudence presents the latest research findings on legal challenges faced by the international regulatory framework, as posed by the increasing deployment of uncrewed vessels at sea. It is the first publication that offers discussions and opinions reflecting a combined international and comparative (especially, eastern) perspective. The contributors from multiple jurisdictions elaborate on legal implications of the use of uncrewed vessels for military, commercial, scientific-research, and law-enforcement purposes from such diverse angles as the law of the sea, international humanitarian law, the law of war, global shipping regulation, marine environment protection, cybersecurity, and artificial intelligence and law.