Together, the two volumes of this book provide a comprehensive review of receptors in the developing nervous system, placing basic and clinical information into perspective and pointing to possible areas for future research. The authors take a contemporary approach emphasizing information derived from the application of cell and molecular biology. Receptors related to growth factors and hormones are discussed in volume I and those related to neurotransmitters in volume II. A number of themes are maintained throughout both volumes: the receptor and the compound interacting with it are considered as a unit - hence relevant compounds are introduced at the start of each chapter; transient receptors are discussed; the possibility that evolving receptors are vital in establishing the framework of pathways or architecture in the brain is discussed; and the implications that alternations in the development of neural receptors may have for the structure and function of the organism are reviewed. Together, the volumes provide an invaluable source of reference for researchers and graduate students in a wide range of basic and clinical disciplines.
This book should be of interest to developmental biologists, pharmacologists, clinical researchers, neuroscientists, and neurologists.