Explaining the innovative, radical, and aggressive approaches towards a more effective and efficient public health care, this definitive guide wraps up the series of seminars, workshops, and publications from Crosstalks - Vrije Universiteit Brussel's university and industry network that aims to bridge the gap between the academic and industrial world. This account examines the information gathered from 2005 to 2008 and discusses the contemporary challenges as well as the advances in medicine. Seeking to generate an open dialog about the world of health care, this compilation brings together voices from academic, political, corporate, and patient communities that want to engage in a collaborative exploration of the future of public health care.