One of the phylogenetically oldest hormones, somatostatin is a regulatory peptide with remarkable characteristics. It is a nonclassical neurotransmitter discovered less than 20 years ago both in the central nervous system and in the gastroenteropancreatic system. It regulates the secretion of both pituitary and digestive hormones, it ensures nutrient homeostasis and it has therapeutic uses. This volume deals withall these aspects.

Contributions by: Y.C. Patel, J. Epelbaum, D.R. Rubinow, C.L. Davis, R.M. Post, V. Schusdziarra, P.N. Maton, R.F. Arakaki