This book presents original results on the leading edge of cancer research. Topics discussed include imaging of chondrosarcoma; novel nutrient mixtures inhibiting chondrosarcoma invasion and metastasis parameters; defective estrogen signaling is the highest risk for breast cancer; review of the cancer genomic landscape; reprogramming of metabolic pathways and cancer stem like cells; promising natural products as anti-cancer agents against neuroblastoma; oncofertility; and molecular mechanisms involved in myelodysplastic syndromes.