This book presents original research results on the leading edge of cancer. Topics discussed include the role of dendritic cells in the priming of cytotoxic T lymphocyte responses; current anti-cancer agents targeting apoptosis and authophagy and clues for future cancer drug discovery; the efficacy of bufadienolides and TCM preparations on in vivo and in vivo cancer models in clinical trials; the role of tetracyclic triterpenes and their glycosides in cancer prevention; adoptive cell therapy at the forefront of cancer immunotherapy; the challenges and promises of targeted chemoprevention; the physical, emotional and social challenges associated with cancer survivorship; bioinformatics tools and resources for cancer diagnosis and drug development; and the history of radical surgery for the treatment of prostate cancer.