Horizons in Cancer Research presents original research results on the leading edge of cancer. Topics discussed include paclitaxel in chemotherapy and neurotoxicity; the role of prostate-specific antigen (PSA) in pathological angiogenesis and prostate tumour growth; second primary cancer in children and adults; CD133 as a cancer stem cell marker; psychosocial oncology; brain metastases and target therapy for DSB repair deficient tumours; and management of recurrent cervical carcinoma.