This book mainly focuses on diversity of brain diseases, such as sleep disorders, major depression disorder, anxiety disorders, epilepsy, cognitive disorders, etc. It introduces the current pathological mechanisms of various diseases from the perspective of basic theories and research; it introduces the clinical evaluation and treatment of the above diseases from the clinical perspective. In addition, the current frontier research on therapeutics of neural stimulation for the above brain disorder was introduced, such as Transcranial electrical stimulation, magnetic stimulation, ultrasonic stimulation, etc., and the therapeutic strategy and stimuli parameters for reference were proposed.