This volume in the highly regarded Diagnostic Pathology series provides a clearer understanding of molecular pathology as it relates to the transformation and pathogenesis of cancer. Diagnostic Pathology: Molecular Oncology is the first reference to apply a practical and clinical approach to examining how molecular mutations affect common medical diseases. Additionally, it identifies the relevant and appropriate molecular tests to perform for a complete work-up in the era of molecular-targeted therapies. Easy to use and packed with outstanding illustrations, this is an essential resource for all pathologists or clinicians who need to keep up with the ever-evolving field of molecular medicine.
Up-to-date information on a variety of topics
Next-generation sequencing for determining gene mutations
Diagnostic use of soft tissue mutations
Use of solid tissue mutations such as EGFR, BRAF, and KRAS for diagnosis and treatment of different carcinomas and melanoma
Interpreting newly found mutations in hematopathology such as MYD88 mutations
Understanding bioinformatics
Guidance on selecting the right test(s) at the right time for the right patient
Comparisons of molecular testing methods (i.e., FISH testing vs. cytogenetics)
More than 2,000 images including H&E stains, immunostains, and FISH images
Expert Consult eBook version included with purchase allows you to search all of the text, figures, and references from the book on a variety of devices