"Advances in Genetics Research" presents original research results on the leading edge of genetics discovery. Each article has been carefully selected in an attempt to present substantial research results across a broad spectrum. In this continuing series compilation, the authors present and discuss varied topical data such as the role of IL-1 in the cytokine network of the body; genetic manipulation of leishmania parasites facilitating the exploration of polyamine biosynthetic pathways as potential therapeutic targets; RNA interference-mediated cell camouflage; identification of RNA in analysis of body fluids stains for forensic purposes; cationic lipid-based nanoparticles for siRNA delivery; Interleukin-1 in osteoarthritis; fungal genetic manipulation using RNA silencing; microglial cathespin B-dependent IL-1B production; role of miRNAs in early embryonic development of drosophila melanogaster; and pHg/pSILBAy vector system for RNA silencing in mycorrhiza via agrobacterium-mediated transformation.