This book constitutes the proceedings of the 20th International Conference on Service-Oriented Computing, ICSOC 2022, held in Seville, Spain, in November -December 2022.The 29 full, 15 short, and 4 vision papers included in this volume were carefully reviewed and selected from 221 submissions. They were organized in topical sections named: ​service modeling and mining; quality of service; microservices; service personalization, recommendation, and crowdsourcing; blockchain; IoT and green computing; services for cloud, edge, and fog computing; artificial intelligence and machine learning for service computing; vision papers.