This book takes an innovative new approach to therapeutic decision-making, providing answers to a range of questions that the busy clinician faces on a daily basis. In a carefully chosen series of discussions, the contributors, all of whom are internationally recognised authorities in their fields, offer their own recommendations for managing difficult problems and offer insights into the value or otherwise of various treatment choices based on their own experience and the available evidence. This book addresses key questions in therapeutic decision making. The evidence-based approach highlights the factors that determine successful outcomes. It also features treatment options for specific patient groups, and presents 'what if' scenarios.