This issue of Clinics in Plastic Surgery takes a critical look at several new treatment methods. The aim of the issue is to view each technique from a factual, scientific point of view and to let surgeons know where each technique stands in regard to indications, contraindications, choosing a patient, how the technique is done, results, and complications. The techniques included are Lipodissolve, Surgisis, Smartlipo, Thermage, fat injection, Juvista, and Aptos thread.