IMS: Medical Neuroscience is designed for 1st- and 2nd-year medical students to be an introduction to neuroscience as it relates to clinical medicine. Although the nervous system can be thoroughly described by listing its cellular components and anatomical connections, a clinical appreciation of neuroscience requires a more integrative approach. In IMS: Medical Neuroscience, the clinical relevance of anatomical features are interwoven throughout the text by incorporating discussions of neurological diseases, syndromes, and clinical signs of neural trauma in the context of specific attributes of nervous system organization. By linking the anatomy to its clinical importance, students take a richer understanding of the nervous system with them as they begin their clinical training.