This two-volume set LNCS 4803/4804 constitutes the refereed proceedings of the five confederated international conferences on Cooperative Information Systems (CoopIS 2007), Distributed Objects and Applications (DOA 2007), Ontologies, Databases and Applications of Semantics (ODBASE 2007), Grid computing, high performance and Distributed Applications (GADA 2007), and Information Security (IS 2007) held as OTM 2007 in Vilamoura, Portugal, in November 2007.