This book discusses initiatives intended to promote strategic flexibility, resilience, sustainability, and information system flexibility and analytics, through AI, HR analytics, employee attrition using perspectives from machine learning, agile competencies, agile organization, digital recruitment, e-governance, cyber security controls, and cyber security risk management. It explores areas such as banking system, medical tourism, pharmaceutical industry, defense sector, online shopping, to name some. It brings different perspectives on how to improve the resilience of human resources in organizations through employee engagement, exploration, experimentation, and so on, to create sustainable organizations. There is also some focus on innovation and environmental sustainability concerns, co-worker support, exploring the linkages, and in one case, culture essentials for Industry 5.0. Divided into three parts, covering a range of topics, contexts, and methods used to understand the relevant issues in flexibility, resilience, and sustainability, thes book is a useful addition to the literature on the topic as well as a practical resource for practitioners. It will be a useful resource for a variety of audiences such as management students and researchers, practicing business managers, consultants, and professional institutions.