This volume contains the proceedings of two conferences on Inverse Problems and Applications, held in 2012, to celebrate the work of Gunther Uhlmann. The first conference was held at the University of California, Irvine, from June 18-22, 2012, and the second was held at Zhejiang University, Hangzhou, China, from September 17-21, 2012. The topics covered include inverse problems in medical imaging, scattering theory, geometry and image processing, and the mathematical theory of cloaking, as well as methods related to inverse problems.