This volume constitutes the refereed proceedings of the 5th Multi-disciplinary International Workshop On Artificial Intelligence, MIWAI 2011, held in Hyderabad, India, in December 2011. The 38 revised full papers presented were carefully reviewed and selected from 71 submissions. The papers cover the multifarious nature of the Artificial Intelligence research domain, ranging from theoretical to real world applications and address topics such as agent-based simulation, agent-oriented software engineering, agents and Web services, agent-based electronic commerce, auctions and markets, AI in video games, computer vision, constraint satisfaction, data mining, decision theory, distributed AI, e-commerce and AI, game theory, internet/www intelligence, industrial applications of AI, intelligent tutoring, knowledge representation and reasoning, machine learning, multi-agent planning and learning, multi-agent systems and their applications, multi-agent systems and evolving intelligence, natural language processing, neural networks, planning and scheduling, robotics, uncertainty in AI, and Web services.