With the EHR (Electronic Health Record) being central to most health informatics applications, several countries have initiated programs for implementing national EHR infrastructures. Building and implementing such a national EHR infrastructure requires an understanding of healthcare standards, coding systems, and standard frameworks, each of which may vary across borders and/or come from a myriad of sources. With this in mind, the authors compiled their study and analysis results in a groundbreaking single-source guide to fill the void in this area for the benefit of others working in similar areas.