This edited book provides an overview of omics technologies and methods for integration across multiple omics layers used in the plant disease diagnosis and developing management strategies. The book concentrates on the prevalence of soil-borne disease management in various important crops with use of different strategies, including host resistance and biological control etc. The special focus is on the resolving practical problems encountered after the resistance development in the pathogens against several chemical pesticides. Further, special attention is given to the emergence of new diseases or the re-emergence of old ones on several crops, and on the results and problems encountered by using microbial inoculants, biofumigation and other non-chemical control methods. This book has 18 contributory chapters from the eminent experts in the field of plant pathology, microbiology and biotechnology working on different aspects of soil-borne diseases of important agricultural crops. This edited volume is of interest and useful to researchers in plant pathology, agriculture sciences, plant genomics ecology, policy makers, also it is a valuable source of reference to the relevant researchers and students globally.