First published in 1960, Richard Harrison Shryock's Medicine and Society in America: 1660–1860 remains a sweeping and informative introduction to the practice of medicine, the education of physicians, the understanding of health and disease, and the professionalization of medicine in the Colonial Era and the period of the Early Republic. Shryock details such developments as the founding of the first medical school in America (at the College of Philadelphia in 1765); the introduction of inoculation against smallpox in Boston in 1721; the creation of the Marine Hospital Service in 1799, under which all merchant marines were required to take out health insurance; and the state of medical knowledge on the eve of the Civil War.