This hugely ambitious volume, worldwide in scope and ranging from antiquity to the present, examines the human encounter with Unreason in all its manifestations, the challenges it poses to society and our responses to it. In twelve chapters organized chronologically from the Bible to Freud, from exorcism to mesmerism, from Bedlam to Victorian asylums, from the theory of humours to modern pharmacology, Andrew Scull writes compellingly about madness, its meanings, its consequences and our various attempts to understand and treat it.