Guiding clinicians toward the most effective treatment regimens, this reference offers detailed coverage of the symptomatology, diagnosis, epidemiology, and etiology of depression. A must-have tool for anyone prescribing psychotropics or performing psychotherapy, this source expertly reviews research and clinical data regarding acute and long-term outcomes, combination therapies, neuroimaging, genetics, and pharmacologic and psychotherapeutic measures to stand as the most complete layout of practices in the management of depression.