Although it is widely recognized that there are significant
variations in the circulation throughout the 24-hour day,
these patterns have often been conceived as nuisance
variables rather than functional differences.
Responses of the circulation are examined here not as stable
phenomena, but as integrated functions highly sensitive to
environmental conditions, and driven by internal and
external pacesetters. In this volume, cardiologists with a
primary interest in hypertension or heart disease,
chronobiologists, and psychologists join together for the
first time to give the reader the opportunity to learn the
extent and clinical significance of these changes from a
chronobiological, behavioral and physiological perspective.

Foreword by: S. Julius