A failed erotic novelist; a hostess of prim sex-toy parties; an artist and a bookshop owner pursued by a demented if harmless stalker; wives, lovers, twin sisters, daughters--all members of the artsy crowd in Omaha, try to hold their families, friendships and personal lives together as they face damaged and broken marriages, and mid-life crises during one whirlwind day that may only be saved by their own children, a timely fire, and a return to their senses. Ashley, a frustrated novelist, teaches a community college class in the writing of erotica, which only seems to turn a magnifying glass on her own marriage woes. June has become filthy rich by selling marital aides at Tupperware-like home parties for a company called Sugar Shop Inc., but despite her wealth, she still longs to reunite with her impoverished ex-husband. Viv, an artist, learns to find creative inspiration, and maybe even a better understanding of herself, from a dirty-minded stalker who reliably sends her startling pictures in the mail every day. Peach and Plum, twin sisters, own a bookstore called Mermaids Singing, where together they attempt to unravel the knots of their own neuroses. All the while, the words and questionable wisdom of a tough-love motivational speaker, known only as Sybil the Guru, echoes throughout all their lives.

The day ends with a few raucous parties that threaten, or promise, to challenge the ways these various women continue to live. As the women struggle for guidance in the face of sheer lunacy, they come to realize that the most useful answers are likely the ones they come up with all on their own.