When parents find themselves alone after their children move out of the house—or when anyone’s loved one moves out of the home—they may experience a very real sense of loneliness, lack of purpose, and even grief. These prayerful reflections on the Joseph story, the incarnation, and the last discourse of Jesus offer comfort and challenge to anyone with an empty nest. The word of God has the power to help empty nesters change, let go, and love anew.