This concise pocket-sized guide is intended primarily for 3rd and 4th year students in their internal medicine rotation. Written by teaching residents, this book takes a simple and straightforward approach to common medical problems. Broad topics like anemia, renal failure, and vasculitis are broken down into manageable pieces. Mnemonics, used primarily as a means of creating extensive differential diagnoses, are followed by step-by-step instructions. Important “Hot Keys”, or clinical pearls, are interspersed at critical junctures throughout the text. New to the Second Edition are sections on hospital-acquired complications, pleural effusions, skin and soft tissue infections, and seizure disorders.