Clinical transplantation is still in the infancy stage with less than 60 years history. Despite recent successes, there are still several unresolved problems. This book tries to tackle some of these problems such as organ shortage, live donation, expanding the donor pool, ethical and legal issues regarding brain death concepts, the consent for donation process, and the use of human tissue for transplantation. The diversity of authors with different backgrounds such as physicians, philosophers, and ethicists, makes this book unique. The book tries to comprehensively discuss different issues from different angles that transplantation faces today. This book has 12 chapters discussing a wide variety of topics related to organ donors and donation.