This 2nd edition provides up-to-date information on the diagnosis and treatment of cancers of the eye and orbit. The 1st edition has been significantly revised. The most recent data with respect to retinoblastoma, rhabdomyosarcoma, and melanoma are included, and there are a number of chapters by new contributors, lending this edition a more broadly based, international character. The presenting signs and symptoms of tumors are outlined, and indications for the various imaging modalities are analyzed. Treatment techniques, together with their results in respect of survival and local tumor control, are described in detail; throughout, special attention is paid to multimodality therapy. Potential complications of radiotherapy are described, and relevant information is provided on the management of radiation effects. The emphasis is on the need for a holistic approach to the patient that recognizes the wider role of irradiation of the eye now that more careful treatment planning is possible.