Matthew Kershaw, a professor and crypto zoologist, on a quest to discover a cryptid wolf species. However, his research plans for the summer are interrupted when he receives an urgent call from an old college friend asking for his help to investigate an attack on a forest ranger in a remote valley deep within the wilderness of the Pacific Northwest. Intrigued by the Ranger's report, describing the wolves that attacked and mauled him as being exceptionally large with strange features. Kershaw believes this might be the cryptid wolf species, he is convinced are the basis for the tales of animal totems, animal spirits, skin-walkers, and their brethren that he's heard about since he was a little boy. Kershaw eagerly accepts the assignment, but he has no idea that life is about to turn treacherous, and he'll soon be in the middle of a conflict between real-life transgenic wolves, Therianthropes, and human-animal hybrids.