This book collects a multidisciplinary range of contributions focusing on the prolific and seminal work of Willem Drees in the fields of philosophy of religion, philosophy of the humanities, and science and theology/religion. Trained in both theoretical physics and theology/philosophy of religion, Drees holds doctoral degrees in both theology and in philosophy and, amongst other distinguished positions, held professorships at the University of Leiden and at the University of Tilburg. Drees was also Editor-in-Chief of Zygon, Journal of Religion & Science, between 2008 and 2018, and served as President of the European Society for the Study of Science and Theology (ESSSAT) between 2002 and 2008. In 2018, he was elected as member of the Royal Holland Society of Sciences and Humanities (KHMW). This contributed volume builds on Drees’ expansive and provocative scholarly contributions, notably around the concept and meaning of naturalism and the humanities to the fields of science and religion, as exemplified by his works Religion, Science and Naturalism (1996) and What Are the Humanities For? (2021). In a time where more and more young people across the globe are entering higher education such cross-disciplinary explorations and (re-)evaluations are vital to the field. Accordingly, by approaching his work from a variety of disciplines this collection illuminates the broad reach of Drees’ work and provides scholars from various fields with many new and rich opportunities avenues for research.